Associate Scientist - Chemistry

Redx Pharma is a clinical-stage biotechnology company focused on the discovery and development of novel, small molecule, highly targeted medicines for the treatment of cancer and fibrotic diseases. The Company has a strong track record of discovering new drug candidates through its core strengths in medicinal chemistry and translational science. Redx's lead oncology product candidate, the Porcupine inhibitor RXC004, being developed as a targeted treatment for Wnt-dependent cancers, is currently undertaking a Phase 2 programme as both a monotherapy and in combination with anti-PD-1. The Company's lead fibrosis product candidate, the selective ROCK2 inhibitor RXC007, is in development for interstitial lung disease and commenced a Phase 2a trial for idiopathic pulmonary fibrosis in October 2022. Redx's third drug candidate, RXC008, a GI-targeted ROCK inhibitor for the treatment of fibrostenotic Crohn's disease, is currently in pre-IND stage.

The Company's accomplishments are evidenced not only by its two wholly-owned Phase 2 clinical-stage product candidates and rapidly expanding pipeline, but also by its strategic transactions, which include significant partnering deals with both AstraZeneca and Jazz Pharmaceuticals.

The Role

Entry level laboratory-based position contributing to the discovery and delivery of novel pharmaceuticals by carrying out research to agreed objectives

Responsibilities

• Undertake the synthesis of compounds to required quality standards, including acquiring and interpretation of analytical data (LCMS, NMR etc)
• Apply knowledge and experience to the interpretation of reactions and analytical data, identify and understand problems encountered
• Clear and accurate recording of experiments in laboratory notebooks
• Propose modifications to the synthetic route or techniques to solve experimental problems
• Develop discipline and drug discovery knowledge through journal and patent literature and via relevant training
• Comply with Redx Health and Safety Policy, relevant safety procedures and COSHH regulations
• Understand and follow the direction of project milestones, timelines, and resources

Requirements

• BSc or MSc with a significant Organic Chemistry component (final-year organic synthesis research project and/or industrial placement as a minimum)
• Experience of practical synthetic organic chemistry
• Knowledge of synthetic organic chemistry

Competencies

• Results orientation
• Innovation & Creativity
• Planning & Organising
• Communication Skills
• Interpersonal skills/Team orientation
• Motivation
• Thoroughness

In return, we will offer you the opportunity to work at an exciting drug discovery company where you will get exposure to a broad range of activities and develop your drug discovery skills.

The closing date for applications will be 10th March 2023.

Job Type: Full-time

Salary: From £25,000.00 per year

Benefits:

• Casual dress
• Company pension
• Cycle to work scheme
• Free parking
• On-site parking
• Sick pay

Schedule:

• Monday to Friday

Supplemental pay types:

• Bonus scheme

Ability to commute/relocate:

• Alderley Park, SK10: reliably commute or plan to relocate before starting work (required)

Education:

• Bachelor's (preferred)

Licence/Certification:

• Right to work in the UK (required)

Work Location: One location